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ABSI, Absci Corporation

Life Sciences Tools & Services capital-intensive UnprofitableNet current asset value

We are a clinical-stage biopharmaceutical company using an AI-native approach to develop differentiated antibody therapeutics.

Our integrated drug creation platform combines Origin-1, our generative design model, with rapid validation using our lab-in-the-loop.

Our lead product candidate, ABS-201, is an anti-prolactin receptor (PRLR) antibody engineered with an extended half-life to support a patient-friendly dosing interval.

Latest annual: FY2025 10-K

ABSI · Absci Corporation

The business

What it sells, where the money comes from, the kind of company it is.

Revenue · FY2025

$3M

−38.2% YoY · −10% 5-yr CAGR

Vital signs · TTM

Cash & investments $131M

Cash burn · annual $97M

Runway 1.3 yrs

The business in brief

read the 10-K →

What this business is and what moves its needle, from its own SEC filings.

Situation: Unprofitable. No meaningful revenue yet; the record is the cash on hand against the burn. Net current asset value. Current assets alone exceed every liability combined, and the surplus is most of the balance sheet: the shape Graham called a net-net.
What moves the needle: Operating margin has run around −2020% through the cycle, the operating line deeply negative — so the lever is the path to a margin at all: revenue growth against the cost curve and the cash runway, not the level of a margin that isn't there yet. Stock-based pay runs about 218% of sales, a real and recurring claim on owners that the GAAP margin understates. On its own account, the filing leans hardest on pricing power & competition, set against the numbers in what the filing emphasizes, below.
Is it a good business?: Return on capital has rarely cleared the cost of capital (median −56%, above 15% in 0 of 5 years). Owner earnings, the cash-based check, have been thin too. This is price-taker territory, where the balance sheet and the cycle matter more than any multiple; the rest is in the 10-K.

Every line is arithmetic on the company's filings, shown in full in the sections below.

The record

Ten years of arithmetic, read across the cycle.

The record, 2020–2025

realized figures from each filing · older years to the left

2020’20	2021’21	2022’22	2023’23	2024’24	2025’25	TTMTTMMar 2026
							Income statement
$5M	$5M	$6M	$6M	$5M	$3M	$2M	RevenueRevenue
115%	602%	706%	662%	798%	n/m	n/m	SG&A / revenueSG&A/rev
239%	932%	n/m	841%	n/m	n/m	n/m	R&D / revenueR&D/rev
($13M)	($75M)	($107M)	($116M)	($109M)	($120M)	($123M)	Operating incomeOp. inc.
−278.3%	n/m	n/m	n/m	n/m	n/m	n/m	Operating marginOp. mgn
($14M)	($101M)	($105M)	($111M)	($103M)	($115M)	($118M)	Net incomeNet inc.
							Cash flow & returns
($11M)	($61M)	($81M)	($65M)	($72M)	($93M)	($97M)	Operating cash flowOp. cash
$1M	$7M	$13M	$14M	$13M	$12M	$11M	DepreciationDeprec.
$2M	$23M	($2M)	$21M	($2M)	($8M)	($8M)	Working capital & otherWC & other
$2M	$38M	$16M	$860K	$404K	$1M	$1M	CapexCapex
45.6%	795.6%	281.5%	15.0%	8.9%	39.5%	60.6%	Capex / revenueCapex/rev
($13M)	($99M)	($98M)	($65M)	($73M)	($94M)	($99M)	Owner earningsOwner earn.
−275.1%	n/m	n/m	n/m	n/m	n/m	n/m	Owner earnings marginOE mgn
($13M)	($99M)	($98M)	($65M)	($73M)	($94M)	($99M)	Free cash flowFCF
−275.1%	n/m	n/m	n/m	n/m	n/m	n/m	Free cash flow marginFCF mgn
$0	$28M	$8M	$0	—	—	$0	AcquisitionsAcquis.
—	-51%	-37%	-82%	-61%	-56%	-58%	ROICROIC
—	-28%	-38%	-63%	-58%	-61%	-69%	Return on equityROE
—	−28%	−38%	−63%	−58%	−61%	−69%	Retained to equityRetained/eq
							Balance sheet
$70M	$253M	$60M	$72M	$112M	$156M	$131M	Cash & investmentsCash+inv
—	—	—	$2M	$0	—	$1M	ReceivablesReceiv.
$2M	$8M	$2M	$2M	$3M	$3M	$9M	Accounts payablePayables
—	—	—	$686K	($3M)	—	($8M)	Operating working capitalOper. WC
$73M	$273M	$187M	$121M	$134M	$150M	$132M	Current assetsCur. assets
$10M	$34M	$30M	$30M	$29M	$23M	$20M	Current liabilitiesCur. liab.
7.3×	8.1×	6.2×	4.1×	4.7×	6.6×	6.6×	Current ratioCurr. ratio
$0	$21M	$21M	$0	—	—	$0	GoodwillGoodwill
$89M	$426M	$321M	$217M	$214M	$216M	$196M	Total assetsAssets
$4M	$4M	$11M	$8M	$4M	$0	$4M	Total debtDebt
($66M)	($249M)	($49M)	($64M)	($108M)	($156M)	($127M)	Net debt / (cash)Net debt
-21.0×	-21.9×	-109.8×	-114.4×	-192.7×	-575.7×	-834.0×	Interest coverageInt. cov.
($89M)	$366M	$274M	$176M	$179M	$189M	$172M	Shareholders’ equityEquity
8.8%	221.8%	218.2%	199.7%	429.0%	654.3%	968.8%	Stock comp / revenueSBC/rev
							Per share
15.5M	49.7M	90.8M	92.0M	110M	137M	153M	Shares out (diluted)Shares
$0.31	$0.10	$0.06	$0.06	$0.04	$0.02	$0.01	Revenue / shareRev/sh
$-0.93	$-2.03	$-1.15	$-1.20	$-0.94	$-0.84	$-0.77	EPS (diluted)EPS
$-0.85	$-1.99	$-1.07	$-0.71	$-0.66	$-0.69	$-0.64	Owner earnings / shareOE/sh
$-0.85	$-1.99	$-1.07	$-0.71	$-0.66	$-0.69	$-0.64	Free cash flow / shareFCF/sh
$0.14	$0.77	$0.18	$0.01	$0.00	$0.01	$0.01	Cap. spending / shareCapex/sh
$-5.77	$7.37	$3.02	$1.91	$1.62	$1.39	$1.12	Book value / shareBVPS

The diluted share count moved ×3.21 into 2021 — shares issued, not a split the totals corroborate — and the per-share figures carry the counts as filed.

The diluted share count moved ×1.83 into 2022 — shares issued, not a split the totals corroborate — and the per-share figures carry the counts as filed.

Per-share growththe realized rate an owner's share compounded

	5-yr	5-yr
Revenue / share	−41.9%/yr	−41.9%/yr
Capital spending / share	−43.5%/yr	−43.5%/yr

The record, charted

FY2020–2025

Each measure over its full record; the current point and the worst year marked.

Share count

137Mpeak FY2025

ROIC

−56%low FY2023

Owner earnings vs. net income

Owner earningsNet income

The accountant's number, and the cash an owner can take; the gap is the tell.

($94M)owner earningsvs.($115M)net incomelow FY2021

Owner-earnings bridge

FY2021–FY2025cash-flow statement, SEC EDGAR →

Net income is the accountant's number; owner earnings is the cash an owner could take out. The walk between them, off the cash-flow statement, and whether the gap is widening or holding.

In fiscal 2025 the business turned a $115M loss into ($94M) of owner earnings: more cash than the profit line showed, after the non-cash charges and the capital it put back in.

	FY2025	FY2024	FY2023	FY2022	FY2021
Reported net income	($115M)	($103M)	($111M)	($105M)	($101M)
Depreciation & amortizationnon-cash charge added back	+$12M	+$13M	+$14M	+$13M	+$7M
Stock-based compensationreal costnon-cash, but a real cost	+$18M	+$19M	+$11M	+$13M	+$11M
Working capital & othertiming of cash in and out, other non-cash items	−$8M	−$2M	+$21M	−$2M	+$23M
Cash from operations	($93M)	($72M)	($65M)	($81M)	($61M)
Capital expenditurecash put back in to keep running and to grow	−$1M	−$404K	−$860K	−$16M	−$38M
Owner earnings	($94M)	($73M)	($65M)	($98M)	($99M)
Owner-earnings marginowner earnings ÷ revenue	-3358%	-1606%	-1145%	-1697%	-2063%

Owner earnings is the cash an owner could pull out without starving the business: operating cash less the capital it must spend to hold its position . The cash-flow statement also adds stock comp back as non-cash, but it is a real cost paid in shares; counted as the expense it is (less $18M), owner earnings is nearer ($112M).

Maintenance capex is estimated as depreciation where a growing business invests above it; free cash flow is the figure the scorecard's free-cash margin reads.

III

Quality & stewardship

Returns, the balance sheet, capital allocation, and pay.

Owner’s Scorecard

FY2025 10-K · source on SEC EDGAR →

Will it survive?

Can it pay its interest? -575.7×

Does not cover its interest

Operating income ($120M) ÷ interest expense $209K

What this means
A full year of operating profit didn't cover the interest bill. This is the zombie zone: the business depends on refinancing, asset sales, or forbearance to service its debt.
How heavy is the debt, net of cash? +$140M

Net cash

Cash $20M + ST investments $124M − debt $4M

What this means
Cash and short-term investments exceed every dollar of debt by $140M, on net the company owes nothing, and can act from strength when others can't. It also holds $12M in longer-dated marketable securities; counting those, it sits at net cash of $152M. Net debt is the leverage figure that matters: the cash is already set against the debt. Strategic or illiquid investments aren't counted here.
How long is cash tied up? —

Not enough data

What this means
The filing data didn't include the inputs for this check.

Is it a good business?

Return on invested capital -56%

Below average through the cycle

5-yr median, range -82%–-37%; -55% latest = NOPAT ($95M) ÷ invested capital $173M

Industry peers: median -47%

What this means
The rate the business earns on the money tied up in it, Buffett's north star, because over time a stock tracks the ROIC beneath it. Above ~15% sustained hints at a moat; a return below the cost of capital (~8%) erodes value as a business grows rather than building it — the test Buffett weighs most. The headline is the median of the last 5 years (it ran -55% most recently), so one peak or trough year doesn't set the verdict. Asset-light businesses (R&D expensed, little capital) read artificially high, pair this with Owner Earnings.
Owner-earnings margin -1697%

Consumes cash through the cycle

6-yr median margin, range -3358%–-275%; latest ($94M) = operating cash ($93M) − maintenance capex $1M

Industry peers: median -670%

What this means
What an owner could take out without starving the business: operating cash less the maintenance capital it must spend to hold its position — Buffett's owner earnings. That's -3358% of revenue this year, a -1697% median across 6 years. Treating stock comp as the real expense it is (less $18M of SBC) leaves ($112M).
Are earnings backed by cash? ($93M)

Loss, and burning cash

Net income ($115M) · cash from operations ($93M)

What this means
The company reported a net loss, so a conversion ratio isn't meaningful. What matters then is whether operations still threw off cash, here, they did not.

How is the cash used?

Where do the earnings go? —

Not enough data

What this means
The filing data didn't include the inputs for this check.
Investing or harvesting? 0.09×

Harvesting

Capex $1M ÷ depreciation $12M

What this means
Descriptive, not a grade. Above ~1× means investing faster than assets wear out (growth, or, sustained for years, today's earnings carrying less depreciation than tomorrow's will). Below means spending less than it's wearing out (efficiency, or a melting asset base). The ratio won't tell you which; the filings will.

Graham’s defensive tests · 2 of 5 met

Graham’s numerical criteria for the defensive investor (The Intelligent Investor, ch. 14), run on the filings. A floor of safety, not a buy signal; many fine modern businesses fail his strictest liquidity rules by design.

Adequate size Miss

Revenue ≥ $2B · $3M

What this means
Big enough to weather a storm. Graham's 1972 floor was ~$100M of sales (≈ $700M today); we use a $2B revenue line as a conservative modern stand-in.
Strong liquidity Pass

Current ratio ≥ 2× · 6.57×

What this means
Current assets at least twice current liabilities, near-term bills covered without touching the business. Strict by design: many cash-rich modern firms run leaner and miss it, holding their cushion in longer-dated securities.
Conservative debt Pass

Debt ≤ working capital · $4M vs $127M WC

What this means
Graham's rule that borrowings not exceed net current assets. Capital-heavy and buyback-heavy firms routinely fail it, read it next to interest coverage, not alone.
Earnings stability Miss

A profit every year (6-yr record) · 6 loss years

What this means
Graham wanted earnings in each of the past ten years, the stability a defensive owner leans on.
Dividend record Miss

Uninterrupted dividends · none paid

What this means
An unbroken dividend was Graham's mark of durability. He wanted twenty years; the filings show about ten, and a single suspension breaks the streak. Non-payers, many fine modern compounders, fall outside his defensive net by design.
Earnings growth —

Earnings +33% over the record · —

What this means
Earnings were negative early in the record, a growth rate isn't meaningful.
Moderate price —

P/E ≤ 15 and P/E × P/B ≤ 22.5 · decided by the price

What this means
Graham's valuation gate, the wall he kept between a sound business and a sound investment. Three-year average earnings are $-0.70/share (latest year $-0.74), the averaged base the calculator's gate runs on, and book value is $1.22/share. Enter a price in “What the price implies” just below for the P/E, P/B, and whether it clears. But this is the rule Buffett outgrew: there's no hard P/E law, and a wonderful business can deserve a far richer multiple if the thesis holds, treat it as the bargain-hunter's floor, not a verdict on the price.

Durability & moat, 2020–2025

Whether the record’s returns held, and what the capital reinvested earned.

Profitable years 0 of 6

What this means
Lost money in 6 year(s), look at what happened there before trusting the average.
Return on capital ≥ 15% 0 of 5 yrs

What this means
A moat shows up as a high return on invested capital that holds year after year, not one good vintage.
Operating margin −1236% → −2906% (3-yr avg ends)

What this means
Through the cycle the operating margin slipped — about −1236% early to −2906% lately, median −2020% — competition or costs are biting in.
Reinvestment, incremental ROIC returns capital

What this means
The capital base barely grew: this business returns cash through dividends and buybacks rather than reinvesting. Judge it on the cash returned, not on compounding.
Worst year 2025 · −4297.0% op. margin

What this means
Operations went underwater in 2025, understand why before trusting the good years.

Does AI threaten the moat?

Moderate contestability

AI is likely to reshape costs and some products here without clearly contesting or sparing the core moat; how the company itself frames it is the tell.

In its own filing A competitive risk, new this year

Its FY2025 10-K names artificial intelligence as a competitive threat, in language that was not in the prior year's filing.

“More specifically, in the field of AI-based drug design and discovery we may face competition from companies attempting to use AI to design therapeutics.”

The question is whether a moat the record shows as durable outlasts a technology that lowers the cost of part of what the firm sells. The durability is read in the record above, the filing's own framing of AI beside it; the industry label decides nothing on its own.

Read from the filing's own risk factors, paired with the industry's structure under its SIC code; the durability is read above, the price below.

All figures as filed; the source filing is linked above.

Current Position

as of the latest quarter, Mar 31, 2026

Can the business pay what it owes this year, off the freshest balance sheet: the quality of the assets, the debt actually coming due, and what a low ratio means here.

Current assets$132M

Cash & short-term investments$126M
Receivables$1M
Other current assets$5M

Current liabilities$20M

Accounts payable$9M
Other current liabilities$11M

Current ratio6.59×all current assets ÷ what's due · Graham looked for 2×

Quick ratio6.59×stricter: inventory excluded

Cash ratio6.28×strictest: cash alone against what's due

Working capital$112Mthe cushion left after near-term bills

Cash runway1.3 yrsthe business is consuming cash; this is how long the cash on hand lasts at that rate

Revenue, latest quarter vs. a year ago−81.8%the freshest read on whether the business is still growing

Current ratio, recent quarters6.5× → 6.6×

Deeper floors

Tangible book value$131Mequity stripped of goodwill & intangibles

Net current asset value$108MGraham's net-net: current assets less all liabilities

Debt incl. operating leases$8M$4M of it operating leases

Deferred revenue$1Mcustomer cash collected before delivery; operating float

From the company's latest filing.

Acquisitions & goodwill

from the balance sheet & the 6-year cash-flow record

Goodwill grows only when a company acquires and falls only when it concedes it overpaid. The size of that bet, the cash put into buying rather than building, and how much has already been written off.

Goodwill & intangibles$42M19% of all assets; the premium carried on the balance sheet for businesses acquired

Against book equity0%goodwill is this share of book equity; the rest is the company’s own retained and paid-in capital

Cash spent acquiring$36Mover 6 years buying other businesses, against $59M of capital spent building

$21M written down across 1 year (2023): goodwill the company has already conceded it overpaid for, charged against earnings. That is roughly 59% of the cash it put into acquisitions over the span. A write-down costs no cash (the cash went out when the deal was signed), but it is management marking its own past judgment to market.

Goodwill, acquired intangibles and equity from the latest balance sheet; acquisition spend and write-downs summed across the 6-year record, from the company's own filings.

Management, ownership & pay

read the proxy →

From the proxy: how much of the business the people running it own, and how they are paid.

Insider ownership10.5%
The stake all directors and executive officers hold together, per the 2026 proxy: skin in the game, the first thing Munger reads.
Stock-based compensation$18M
The slice of the business handed to employees in shares this year, 654% of revenue. Buffett's oldest accounting fight: this is compensation, compensation is an expense, real whether or not the headline earnings admit it. One trap: the cash-flow statement adds SBC back, so the operating cash, and the owner earnings drawn from it, are flattered by exactly this amount; counted as the cost it is, what an owner keeps is lower.

What an owner would ask, FY2025

read the 10-K →

Which reported numbers are a judgment call?
Management names Revenue recognition as critical estimates
each rests partly on management's judgment; the filing's note sets out the assumptionsverify →

The questions the record and the charts do not answer on their own; each carries the figure and the place to look.

Peers, nearest by economic model

No close industry peers in the catalog yet, so these are the nearest by economic model (capital-intensive), compared on owner economics. Each figure is a through-cycle median, so a peak or trough year can’t distort it; the group median at the foot is the line to read each against.

Company	Revenue	Gross margin	Op. margin	ROIC	Owner earn. margin
ATEXAnterix Inc.	$7M	-47%	-671.2%	-24%	-427%
BMNPBitmine Immersion Technologies, Inc.	$6M	—	-224.0%	-32%	-139%
ABATAmerican Battery Technology Company	$4M	—	-979.5%	-46%	-734%
IEIvanhoe Electric Inc.	$3M	65%	-3501.0%	-65%	-2787%
ABSIAbsci Corporation	$3M	—	-1938.8%	-56%	-1651%
ALOYREalloys Inc.	$2M	45%	-133.6%	-48%	-71%
AVXAvax One Technology Ltd.	$2M	96%	-37998.5%	-55%	-670%
AVRAnteris Technologies Global Corp.	$2M	70%	-4908.2%	—	-4169%
Group median	—	—	-1459.2%	-48%	-702%

The price

What a price has to assume.

What the price implies

reverse-DCF

Absci Corporation is profitable, but owner earnings are negative this year because capital spending currently outruns operating cash, a build-out, so the owner-earnings reverse-DCF has no positive base to grow. We read the price from both ends instead: type a price to see the steady-state profitability it demands, then set the mature margin you would believe and weigh the two against each other. Nothing leaves your browser unless you enter it in your notebook.

Today’s price $

The assumptions Required return 9% Years to get there 10 Revenue growth 0%

Revenue, delivered−8%/yr’20→’25

Mature owner-earnings margin 15%

Enter a price to run it.

Owner earnings it must reach—

Margin the price demands—

Owner-earnings margin today−5365%

Two reads of one future. From your price: the owner earnings the company must reach, valued at a mature multiple and discounted back at your rate, expressed as the margin it implies on revenue grown at your rate. From your belief: the mature margin you would credit, set on the dial above. When the margin the price demands runs above the one you would believe, you are paying for a future taken on faith. For a deep cyclical at a trough, normalized through-cycle earnings are the better lens; this mode is for the genuinely unprofitable, and for the profitable business whose capital spending currently outruns its cash.

Weigh ABSI against another business →

Cite: Owner Scorecard, "Absci Corporation (ABSI), the owner's record," https://ownerscorecard.com/c/ABSI, data as of 2026-07-09.

Manual order: ← ABR its page in the Manual ABT →

Industry order: ← A the Life Sciences Tools & Services chapter AVTR →