Owner Scorecard


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ONC, BeOne Medicines Ltd.

Pharmaceuticals consumer brand

We are a leading global oncology company discovering and developing innovative treatments that are more accessible to cancer patients worldwide.

Despite being the third entrant to the market, BRUKINSA became the global market leader across B-cell malignancies in 2025.

BRUKINSA generated $3.9 billion in sales in 2025, is approved in over 75 markets and has launched in many key markets, including Europe, Japan, Korea and Brazil.

Latest annual: FY2025 10-K
ONC · BeOne Medicines Ltd.
I

The business

What it sells, where the money comes from, the kind of company it is.

Revenue · FY2025
$5.3B
+40.2% YoY · 77% 5-yr CAGR
Vital signs · TTM, with 5-yr average
Revenue $5.7B 5-yr avg $2.8B
Gross margin 94% 5-yr avg 83%
Operating margin 12.0% 5-yr avg −60.9%
ROIC 51% 5-yr avg −49%
Owner-earnings margin 19% 5-yr avg −53%
Free cash flow margin 19% 5-yr avg −66%

The business in brief

read the 10-K →

What this business is and what moves its needle, from its own SEC filings.

What moves the needle
Operating margin has run around −126% through the cycle on a 86% gross margin, the operating line in the red even at its best — so the lever is whether the spending below the gross line can come down enough to clear a profit: revenue growth against the cost curve, and the cash runway until it does. Capital spending runs about 22% of sales, well above depreciation, so the return earned on what it sinks into that plant weighs as much as the margin. Read this kind of business on the pipeline against the patent cliff, and pricing. On its own account, the filing leans hardest on pricing power & competition, set against the numbers in what the filing emphasizes, below.
Is it a good business?
Return on capital has rarely cleared the cost of capital (median −46%, above 15% in 1 of 10 years). Owner earnings, the cash-based check, have been thin too. This is price-taker territory, where the balance sheet and the cycle matter more than any multiple; the rest is in the 10-K.

Every line is arithmetic on the company's filings, shown in full in the sections below.

Where the money comes from

read the 10-K →

50% of revenue comes from outside the United States.

Revenue by geography, FY2025
  • United States50%$2.9B
  • China29%$1.7B
  • Europe11%$611M
  • Other3%$172M

From the segment footnote of the company's own 10-K. Shares are of total revenue; the profit bar shows each segment's share of segment operating profit, before unallocated corporate costs.

II

The record

Ten years of arithmetic, read across the cycle.

The record, 2016–2025

realized figures from each filing · older years to the left
2016’162017’172018’182019’192020’202021’212022’222023’232024’242025’25TTMTTMMar 2026
Income statement
$1M$238M$198M$428M$309M$1.2B$1.4B$2.5B$3.8B$5.3B$5.7BRevenueRevenue
100%98%86%83%77%86%80%94%Gross marginGross mgn
n/m26%99%91%194%84%90%61%48%39%38%SG&A / revenueSG&A/rev
n/m113%343%217%419%124%116%72%51%40%38%R&D / revenueR&D/rev
($117M)($98M)($706M)($960M)($1.7B)($1.4B)($1.8B)($1.2B)($568M)$447M$686MOperating incomeOp. inc.
n/m−41.3%−356.1%−224.2%−536.7%−122.3%−126.4%−49.1%−14.9%8.4%12.0%Operating marginOp. mgn
($119M)($93M)($674M)($949M)($1.6B)($1.5B)($2.0B)($882M)($645M)$287M$513MNet incomeNet inc.
Cash flow & returns
($90M)$13M($548M)($750M)($1.3B)($1.3B)($1.5B)($1.2B)($141M)$1.1B$1.3BOperating cash flowOp. cash
$2M$5M$10M$19M$32M$46M$66M$88M$172M$142M$150MDepreciationDeprec.
$17M$58M$29M$46M$126M($128M)$138M($731M)($109M)$188M$83MWorking capital & otherWC & other
$24M$46M$70M$90M$118M$263M$325M$562M$493M$186M$170MCapexCapex
n/m19.5%35.5%20.9%38.0%22.4%23.0%22.9%12.9%3.5%3.0%Capex / revenueCapex/rev
($91M)$8M($558M)($769M)($1.3B)($1.3B)($1.6B)($1.2B)($312M)$986M$1.1BOwner earningsOwner earn.
n/m3.4%−281.6%−179.6%−425.8%−114.4%−110.4%−50.6%−8.2%18.5%19.4%Owner earnings marginOE mgn
($113M)($34M)($618M)($840M)($1.4B)($1.6B)($1.8B)($1.7B)($633M)$942M$1.1BFree cash flowFCF
n/m−14.1%−311.8%−196.1%−453.6%−132.8%−128.7%−69.9%−16.6%17.6%19.4%Free cash flow marginFCF mgn
-33%-17%-52%-177%-44%-48%-134%-76%-26%37%51%ROICROIC
-34%-14%-39%-99%-42%-24%-46%-25%-19%7%11%Return on equityROE
−34%−14%−39%−99%−42%−24%−46%−25%−19%7%11%Retained to equityRetained/eq
Balance sheet
$368M$838M$1.8B$983M$4.7B$6.6B$4.5B$3.2B$2.6B$4.5B$4.8BCash & investmentsCash+inv
$29M$41M$71M$60M$483M$173M$358M$676M$865M$938MReceivablesReceiv.
$11M$16M$29M$89M$243M$282M$416M$495M$608M$682MInventoryInvent.
$12M$70M$113M$122M$232M$262M$295M$315M$405M$479M$424MAccounts payablePayables
($29M)($56M)($23M)($82M)$463M$161M$459M$766M$994M$1.2BOperating working capitalOper. WC
$374M$913M$1.9B$1.2B$5.0B$7.6B$5.2B$4.2B$4.0B$6.2B$6.6BCurrent assetsCur. assets
$35M$150M$246M$310M$1.1B$1.6B$1.5B$1.8B$2.2B$1.8B$1.8BCurrent liabilitiesCur. liab.
10.7×6.1×7.9×3.8×4.6×4.8×3.5×2.3×1.8×3.4×3.6×Current ratioCurr. ratio
$109K$109K$109K$109K$109K$109K$109KGoodwillGoodwill
$406M$1.0B$2.2B$1.6B$5.6B$8.5B$6.4B$5.8B$5.9B$8.2B$8.6BTotal assetsAssets
$17M$18M$50M$83M$519M$630M$538M$886M$1.0B$1.0B$1.1BTotal debtDebt
($351M)($819M)($1.7B)($899M)($4.1B)($6.0B)($4.0B)($2.3B)($1.6B)($3.5B)($3.7B)Net debt / (cash)Net debt
-276.7×-26.1×7.7×8.2×Interest coverageInt. cov.
$353M$670M$1.7B$962M$3.9B$6.1B$4.4B$3.5B$3.3B$4.4B$4.8BShareholders’ equityEquity
993.0%18.0%44.0%31.3%59.4%20.5%21.4%15.0%11.6%9.6%9.4%Stock comp / revenueSBC/rev
Per share
404M543M721M781M1.09B1.21B1.34B1.36B1.37B1.47B1.51BShares out (diluted)Shares
$0.00$0.44$0.28$0.55$0.28$0.98$1.06$1.81$2.78$3.62$3.81Revenue / shareRev/sh
$-0.30$-0.17$-0.93$-1.22$-1.50$-1.21$-1.49$-0.65$-0.47$0.19$0.34EPS (diluted)EPS
$-0.23$0.01$-0.77$-0.98$-1.21$-1.12$-1.17$-0.92$-0.23$0.67$0.74Owner earnings / shareOE/sh
$-0.28$-0.06$-0.86$-1.08$-1.29$-1.29$-1.36$-1.27$-0.46$0.64$0.74Free cash flow / shareFCF/sh
$0.06$0.09$0.10$0.11$0.11$0.22$0.24$0.41$0.36$0.13$0.11Cap. spending / shareCapex/sh
$0.87$1.23$2.41$1.23$3.57$5.08$3.27$2.61$2.43$2.96$3.16Book value / shareBVPS
Per-share growththe realized rate an owner's share compounded
9-yr5-yr
Revenue / share+123.1%/yr+66.3%/yr
Capital spending / share+9.0%/yr+3.1%/yr
Book value / share+14.5%/yr−3.7%/yr

The record, charted

FY2016–2025

Each measure over its full record; the current point and the worst year marked.

Share count
1.5Bpeak FY2025
ROIC
37%low FY2019
Gross margin
80%low FY2020

Owner earnings vs. net income

Owner earningsNet income

The accountant's number, and the cash an owner can take; the gap is the tell.

$986Mowner earningsvs.$287Mnet incomelow FY2022

Net income is the accountant's number; owner earnings is the cash an owner could take out. The walk between them, off the cash-flow statement, and whether the gap is widening or holding.

In fiscal 2025 the business earned $986M of owner earnings, the operating cash left after the $142M it takes just to hold its position. It put $44M more into growth; free cash flow, after that spending, was $942M.

Reported net income$287M
Owner earnings$986M · 18% of revenue
FY2025FY2024FY2023FY2022FY2021
Reported net income$287M($645M)($882M)($2.0B)($1.5B)
Depreciation & amortizationnon-cash charge added back+$142M+$172M+$88M+$66M+$46M
Stock-based compensationreal costnon-cash, but a real cost+$511M+$442M+$368M+$303M+$241M
Working capital & othertiming of cash in and out, other non-cash items+$188M−$109M−$731M+$138M−$128M
Cash from operations$1.1B($141M)($1.2B)($1.5B)($1.3B)
Maintenance capital expenditurethe spending needed just to hold position and volume−$142M−$172M−$88M−$66M−$46M
Owner earnings$986M($312M)($1.2B)($1.6B)($1.3B)
Growth capital expenditurediscretionary; spent to get bigger, not to stand still−$44M−$321M−$474M−$259M−$216M
Free cash flow$942M($633M)($1.7B)($1.8B)($1.6B)
Owner-earnings marginowner earnings ÷ revenue18%-8%-51%-110%-114%

Owner earnings is the cash an owner could pull out without starving the business: operating cash less the maintenance capital it must spend to hold its position (here about $142M, roughly its depreciation, the rate its assets wear out). The other $44M of its capital spending is growth it chose, not upkeep it owed; charged only with the maintenance it must do, the business earns well more than the year's free cash flow shows. The cash-flow statement also adds stock comp back as non-cash, but it is a real cost paid in shares; counted as the expense it is (less $511M), owner earnings is nearer $475M.

Maintenance capex is estimated as depreciation where a growing business invests above it; free cash flow is the figure the scorecard's free-cash margin reads.

III

Quality & stewardship

Returns, the balance sheet, capital allocation, and pay.

Owner’s Scorecard

FY2025 10-K · source on SEC EDGAR →

Will it survive?

  • Comfortable
    Operating income $447M ÷ interest expense $58M
    What this means

    Operating profit covers interest with the kind of margin Graham wanted for a defensive holding. Necessary, not sufficient, it says solvent, not cheap.

  • Net cash
    Cash $4.5B + ST investments $3M − debt $1.0B
    What this means

    Cash and short-term investments exceed every dollar of debt by $3.5B, on net the company owes nothing, and can act from strength when others can't. Net debt is the leverage figure that matters: the cash is already set against the debt. Strategic or illiquid investments aren't counted here.

  • Long (60+ days)
    DSO 59 + DIO 775 − DPO 610 days
    What this means

    Days cash is tied up between paying suppliers and collecting from customers. Lower is better; a long cycle means growth itself eats cash.

Is it a good business?

  • Below average through the cycle
    10-yr median, range -177%–37%; 37% latest = NOPAT $308M ÷ invested capital $833M
    Industry peers: median 1%
    What this means

    The rate the business earns on the money tied up in it, Buffett's north star, because over time a stock tracks the ROIC beneath it. Above ~15% sustained hints at a moat; a return below the cost of capital (~8%) erodes value as a business grows rather than building it — the test Buffett weighs most. The headline is the median of the last 10 years (it ran 37% most recently), so one peak or trough year doesn't set the verdict. Asset-light businesses (R&D expensed, little capital) read artificially high, pair this with Owner Earnings.

  • Positive this year, negative across the cycle
    latest $986M = operating cash $1.1B − maintenance capex $142M (positive this year), after an earlier loss stretch (10-yr median -114%)
    Industry peers: median 6%
    What this means

    What an owner could take out without starving the business: operating cash less the maintenance capital it must spend to hold its position — Buffett's owner earnings. That's 18% of revenue this year, a -114% median across 10 years. Treating stock comp as the real expense it is (less $511M of SBC) leaves $475M.

  • Cash-backed
    Cash from ops $1.1B ÷ net income $287M
    What this means

    How much of reported profit showed up as operating cash. Above 1× is reassuring; well below suggests earnings lean on accruals. One year is noisy, growth and working-capital swings distort it, and this is operating cash, not free cash. Watch the multi-year trend.

How is the cash used?

  • Not enough data
    What this means

    The filing data didn't include the inputs for this check.

  • Investing or harvesting? 1.31×
    Expanding
    Capex $186M ÷ depreciation $142M
    What this means

    Descriptive, not a grade. Above ~1× means investing faster than assets wear out (growth, or, sustained for years, today's earnings carrying less depreciation than tomorrow's will). Below means spending less than it's wearing out (efficiency, or a melting asset base). The ratio won't tell you which; the filings will.

Graham’s defensive tests · 3 of 5 met

Graham’s numerical criteria for the defensive investor (The Intelligent Investor, ch. 14), run on the filings. A floor of safety, not a buy signal; many fine modern businesses fail his strictest liquidity rules by design.

  • Adequate size Pass
    Revenue ≥ $2B · $5.3B
    What this means

    Big enough to weather a storm. Graham's 1972 floor was ~$100M of sales (≈ $700M today); we use a $2B revenue line as a conservative modern stand-in.

  • Strong liquidity Pass
    Current ratio ≥ 2× · 3.41×
    What this means

    Current assets at least twice current liabilities, near-term bills covered without touching the business. Strict by design: many cash-rich modern firms run leaner and miss it, holding their cushion in longer-dated securities.

  • Conservative debt Pass
    Debt ≤ working capital · $1.0B vs $4.4B WC
    What this means

    Graham's rule that borrowings not exceed net current assets. Capital-heavy and buyback-heavy firms routinely fail it, read it next to interest coverage, not alone.

  • Earnings stability Miss
    A profit every year (10-yr record) · 9 loss years
    What this means

    Graham wanted earnings in each of the past ten years, the stability a defensive owner leans on.

  • Dividend record Miss
    Uninterrupted dividends · none paid
    What this means

    An unbroken dividend was Graham's mark of durability. He wanted twenty years; the filings show about ten, and a single suspension breaks the streak. Non-payers, many fine modern compounders, fall outside his defensive net by design.

  • Earnings growth
    Earnings +33% over the record ·
    What this means

    Earnings were negative early in the record, a growth rate isn't meaningful.

  • Moderate price
    P/E ≤ 15 and P/E × P/B ≤ 22.5 · decided by the price
    What this means

    Graham's valuation gate, the wall he kept between a sound business and a sound investment. Three-year average earnings are $-0.29/share (latest year $0.20), the averaged base the calculator's gate runs on, and book value is $3.02/share. Enter a price in “What the price implies” just below for the P/E, P/B, and whether it clears. But this is the rule Buffett outgrew: there's no hard P/E law, and a wonderful business can deserve a far richer multiple if the thesis holds, treat it as the bargain-hunter's floor, not a verdict on the price.

Durability & moat, 2016–2025

Whether the record’s returns held, and what the capital reinvested earned.

  • Profitable years 1 of 10
    What this means

    Lost money in 9 year(s), look at what happened there before trusting the average.

  • Return on capital ≥ 15% 1 of 10 yrs
    What this means

    A moat shows up as a high return on invested capital that holds year after year, not one good vintage.

  • Operating margin −3779% → −19% (3-yr avg ends)

    In the filing’s words The words confirm the number: the filing says price increases held their volume, and the margin widened with them — Buffett’s strongest mark of pricing power.

    What this means

    Through the cycle the operating margin widened — about −3779% early to −19% lately, median −126% — pricing power intact or improving.

  • Reinvestment, incremental ROIC −18%
    What this means

    Reinvested capital came back at a negative incremental return over this window — the invested base grew while operating profit did not. The filings show where it went.

  • Worst year 2016 · −10940.2% op. margin
    What this means

    Operations went underwater in 2016, understand why before trusting the good years.

Does AI threaten the moat?

Low contestability

The moat is physical, regulated or balance-sheet-funded, the kind AI cuts costs within but does not contest.

In its own filing Named as a competitive risk

Its FY2025 10-K names artificial intelligence as a competitive threat.

“If the analyses that artificial intelligence applications assist in producing are deficient or inaccurate, we could be subjected to competitive harm, potential legal liability, and brand or reputational harm.”

AI is unlikely to contest a moat that is physical, regulated or balance-sheet-funded; here it reads more as a cost tool than a threat, and the company is using it that way.

Read from the filing's own risk factors, paired with the industry's structure under its SIC code; the durability is read above, the price below.

All figures as filed; the source filing is linked above.

Current Position

as of the latest quarter, Mar 31, 2026

Can the business pay what it owes this year, off the freshest balance sheet: the quality of the assets, the debt actually coming due, and what a low ratio means here.

Current assets$6.6B
  • Cash & short-term investments$4.8B
  • Receivables$938M
  • Inventory$682M
  • Other current assets$187M
Current liabilities$1.8B
  • Debt due within a year$116M
  • Accounts payable$424M
  • Other current liabilities$1.3B
Current ratio3.64×all current assets ÷ what's due · Graham looked for 2×
Quick ratio3.27×stricter: inventory excluded
Cash ratio2.65×strictest: cash alone against what's due
Working capital$4.8Bthe cushion left after near-term bills
Debt due this year vs. cash$116M due · $4.8B cash covered by cash on hand, no refinancing forced · both figures from the Mar 31, 2026 balance sheet
Revenue, latest quarter vs. a year ago+35.5%the freshest read on whether the business is still growing
Current ratio, recent quarters2.0× → 3.6×
Deeper floors
Tangible book value$4.7Bequity stripped of goodwill & intangibles
Net current asset value$2.8BGraham's net-net: current assets less all liabilities
Debt incl. operating leases$1.1B$70M of it operating leases
Deferred revenue$300Kcustomer cash collected before delivery; operating float

From the company's latest filing.

Management, ownership & pay

read the proxy →

From the proxy: how much of the business the people running it own, and how they are paid, beside what the business earned for its owners in the same years.

Fiscal yearChief executivePay, as filed“Actually paid”Owner earnings
2021John V. Oyler$16.7M$22.9M($1.3B)
2022John V. Oyler$18.0M$11.2M($1.6B)
2023John V. Oyler$18.9M$11.4M($1.2B)
2024John V. Oyler$20.8M$15.0M($312M)
2025John V. Oyler$17.9M$60.7M$986M

Both pay figures are the company’s own, from the pay-versus-performance table its proxy statement files. “As filed” is the Summary Compensation Table total: salary, bonus, and equity awards at their value on the day of grant. “Actually paid” is the SEC’s prescribed recalculation, which re-marks those equity awards to what they became as they vested; it can swing far above or below the filed figure in either direction, and negative years occur. Owner earnings are the whole business's, from the record above, for the same fiscal years.

  • Stock-based compensation$511M

    The slice of the business handed to employees in shares this year, 10% of revenue, equal to 114% of operating profit. Buffett's oldest accounting fight: this is compensation, compensation is an expense, real whether or not the headline earnings admit it. One trap: the cash-flow statement adds SBC back, so the operating cash, and the owner earnings drawn from it, are flattered by exactly this amount; counted as the cost it is, what an owner keeps is lower.

What an owner would ask, FY2025

read the 10-K →
  • Which reported numbers are a judgment call?
    Management names Revenue recognition, Income taxes as critical estimates

    each rests partly on management's judgment; the filing's note sets out the assumptionsverify →

The questions the record and the charts do not answer on their own; each carries the figure and the place to look.

Peers, Pharmaceuticals

The same industry, side by side on owner economics. Each figure is a through-cycle median, so a peak or trough year can’t distort it; the group median at the foot is the line to read each against.

CompanyRevenueGross marginOp. marginROICOwner earn. margin
OGNOrganon$6.2B62%25.0%17%12%
ONCBeOne Medicines Ltd.$5.3B86%-124.4%-46%-112%
ELANElanco Animal Health Incorporated$4.7B54%-3.2%-1%4%
JAZZJazz Pharmaceuticals$4.3B16.8%8%35%
PRGOPerrigo Company plc$4.3B36%3.9%1%6%
ALNYAlnylam$3.7B86%-126.0%-83%-107%
BMRNBioMarin$3.2B78%-1.7%-1%1%
AMRXAmneal Pharmaceuticals Inc.$3.0B37%7.9%3%9%
Group median62%1.1%0%5%
IV

The price

What a price has to assume.

What the price implies

reverse-DCF

Type today's close and see the owner-earnings growth you'd have to believe to justify it, beside what BeOne Medicines Ltd. has delivered.

$
Base

The assumptions

9.0% = the 4.55% 10-year Treasury (Jul 15, 2026) + 4.45 points of equity premium. The rate you require is yours to set.

Enter a price above to run it.

Implied by the price
Owner-earnings growth, delivered
Owner-earnings yield
P/E (3-yr earnings ’23–’25)
P/B
Graham’s price gate

Graham capped the multiple at 15×; Buffett and Munger let that rule go: a wonderful business can deserve 50× if the thesis holds. The gate marks the bargain-hunter's floor.

Against a high-grade bond: Graham’s yardstick bond yield%

Prefilled with the 10-year Treasury (4.55%, as of Jul 15, 2026). Edit it for today’s exact figure, or a AAA corporate yield.

Graham measured a stock against the bond you could own instead, the heart of his margin of safety. Enter a price above to weigh the owner-earnings yield against this bond.

Free cash flow $1.1B on 1445M shares outstanding, per the 10-Q cover, as of 2026-04-30; net cash $3.7B. The if-converted diluted count is 1505M, 4% above the shares outstanding: the dilution overhang (convertibles, options) a buyer inherits. The base is the latest year by default; Normalize values it on the through-cycle median owner-earnings margin (to avoid paying on a peak year). Net of stock comp treats option pay as the expense it is. Capex ($170M) runs well above depreciation ($150M), so this is a build-out; Steady-state swaps total capex for maintenance (≈ depreciation), lifting the base to about $1.1B, the cash it would throw off if it stopped expanding. The dials set the multiple a growth belief justifies; the price, and every dollar on this page, is yours.

Cite: Owner Scorecard, "BeOne Medicines Ltd. (ONC), the owner's record," https://ownerscorecard.com/c/ONC, data as of 2026-07-09.

Manual order: ← ONBPP its page in the Manual ONDS →

Industry order: ← OMER the Pharmaceuticals chapter OPK →